Failure to detect abnormal fatty acid profiles in serum lipoproteins in Friedreich's ataxia
✍ Scribed by Janet L. Walker; Susan Chamberlain; Dr Norman Robinson
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 290 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0364-5134
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✦ Synopsis
Abstract
A recent report indicated an association between the spinocerebellar degeneration of Friedreich's ataxia and abnormal fatty acid profiles of the cholesterol ester fraction in both total plasma and high‐density lipoprotein. In an effort to substantiate these findings in lipoproteins, we estimated fatty acid profiles of total high‐density lipoprotein and the cholesterol esters of high‐ and low‐density lipoproteins. Those profiles in 10 Friedreich's ataxia patients compared well with previously reported normal values and did not differ significantly from results in 10 age‐matched controls.