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Failure to confirm genetic association of the CHI3L1 gene with schizophrenia in Japanese and Chinese populations

✍ Scribed by Kazuo Yamada; Eiji Hattori; Yoshimi Iwayama; Tomoko Toyota; Tetsuo Ohnishi; Yasuhide Iwata; Kenji J. Tsuchiya; Genichi Sugihara; Mitsuru Kikuchi; Yuji Okazaki; Takeo Yoshikawa

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 287 KB
Volume: 150B
Category: Article
ISSN: 1552-4841
DOI: 10.1002/ajmg.b.30847

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## Abstract The chromosome 1q23.3 region, which includes the __RGS4__ gene has been implicated in genetic susceptibility to schizophrenia by two linkage studies with lod scores of 6.35 and 3.20 and with positive lod between 2.00 and 3.00 scores in several other studies. Reduced post mortem __RGS4__