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Failure qf phenobarbital to increase bilirubin production in the rat

โœ Scribed by Christian Gisselbrecht; Paul D. Berk

Book ID
115771913
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
911 KB
Volume
23
Category
Article
ISSN
0006-2952

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Effects of phenobarbital on bilirubin me
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โœ Arnold N. Cohen; Jaime Kapitulnik; J. Donald Ostrow; Eugene A. Zenone; Cecile Co ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 810 KB

Jaundiced Gunn rats, treated with phenobarbital (60 mg per kg i.p. for 7 to 10 days) showed 25 and 36% decreases in mean plasma bilirubin levels in two experiments (p < 0.01). Kinetic studies with tracer 14C-bilirubin revealed that there was no change in bilirubin turnover or total pool size due to