Failure of long-term administration of zopiclone and zolpidem to induce tolerance in mice
β Scribed by Mariangela Serra; Alessandra Concas; Giovanni Biggio
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 539 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0893-6609
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Treatment of HeLa cells with aphidicolin at 5 or 0.5 mg/ml induced cell cycle arrest at G 1 /S or G 2 /M phase, respectively, and was accompanied by unbalanced cell growth. Long-term administration of aphidicolin (more than 48 h) resulted in noticeable loss of reproductive capacity though cells were
## Abstract Dichoroacetate (DCA) and trichloroacetate (TCA) were found to be hepatotoxic and hepatocarcinogenic in rodents. To investigate the role of oxidative stress in the longβterm hepatotoxicity of the compounds, groups of mice were administered 7.7, 77, 154 and 410βmgβkg^β1^ per day, of eithe
## Abstract ## Background __In utero__ gene transfer may provide advantages for the correction of congenital genetic disorders. In the present study we compare the ability of adenovirus (AdCMVLacZ), and two serotypes of adenoβassociated virus (AAVCMVLacZ serotypes 2 and 2/5), to target cardiac and