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Failure of intravenous immunoglobulin (IVIg) therapy in experimental autoimmune neuritis (EAN) of the Lewis rat

✍ Scribed by U Enders; K.V Toyka; H.-P Hartung; R Gold


Book ID
117337477
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
561 KB
Volume
76
Category
Article
ISSN
0165-5728

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## Abstract Myelin‐sensitized T‐ and B‐cells (lymph node cells) induced experimental autoimmune neuritis (EAN) in Lewis rats after passive transfer to naive recipients. After 6 days, all recipient rats developed tail paresis that progressed to limb paresis within 12–72 h. Progressive nerve conducti