Combination therapy with methotrexate, v
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Alvaro Aguayo; Jorge Cortes; Deborah Thomas; Sherry Pierce; Michael Keating; Hag
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Article
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1999
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John Wiley and Sons
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English
β 72 KB
π 2 views
BACKGROUND. L-asparaginase in combination with methotrexate has synergistic antileukemic activity in a schedule-dependent fashion. A new preparation of L-asparaginase, polyethylene-glycol conjugated (PEG)-asparaginase, is a pharmacologically different formulation of L-asparaginase with distinct prop