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Failure of 2-mercaptoethane sulphonate sodium (mesna) to protect against ifosfamide nephrotoxicity

✍ Scribed by Sangster, Graeme; Kaye, Stanley B.; Calman, Kenneth C.; Dalton, Joan F.

Book ID
123219750
Publisher
Elsevier Science
Year
1984
Weight
169 KB
Volume
20
Category
Article
ISSN
0277-5379

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## Abstract Acetaminophen, a widely used analgesic and antipyretic, is known to cause hepatic and renal injury in humans and experimental animals when administered in high doses. It was reported that these toxic effects of acetaminophen are due to oxidative reactions that take place during its meta