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Failure of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) to inhibit soluble guanylyl cyclase in rat ventricular cardiomyocytes

✍ Scribed by Jörg W Wegener; Ellen I Closs; Ulrich Förstermann; Hermann Nawrath


Book ID
110004356
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
186 KB
Volume
127
Category
Article
ISSN
0007-1188

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1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-
✍ Han Gil Lee; So Young Kim; Du Sik Kim; Su Ryeon Seo; Syng-Ill Lee; Dong Min Shin 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

## Abstract The effect of the potent soluble guanylyl cyclase (sGC) inhibitor 1__H__‐[1,2,4]oxadiazolo[4,3‐__a__]quinoxalin‐1‐one (ODQ) on neurite outgrowth and retraction was investigated in PC12 cells and SH‐SY5Y human neuroblastoma cells. ODQ inhibited neurite outgrowth and triggered neurite ret