Failed allografts and causes of death after orthotopic liver transplantation from 1985 to 1995: Decreasing prevalence of irreversible hepatic allograft rejection
✍ Scribed by Ludwig, Jurgen ;Hashimoto, Etsuko ;Porayko, Michael K. ;Therneau, Terry M.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1996
- Tongue
- English
- Weight
- 559 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1074-3022
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✦ Synopsis
liver trransplantations in 515 patients. The most common indication for liver transplantation was primary sclerosing cholangitis (PSC), followed by primary biliary cirrhosis (PBC), and cryptogenic cirrhosis. In 59 patients, a total of 69 single or repeated retransplantations became necessary. Vascular complications necessitated retransplantation in 35 cases, followed by irreversible rejection in 16 cases, and primary graft failure in 8 cases. Ninety-nine patients died, 25 of them after one or more retransplantations. Infectious complicationls caused death in 38 cases, followed by graft-related complications (excluding rejection) in 22 cases, noninfectious systemic diseases such as intracerebral hemorrhage (21 cases), malignancies in 13 cases, and irreversible rejecn an attempt to determine the changing impact of I rejection in relation to other complications after liver transplantation, we reviewed the pathology files from the beginning of the Mayo Clinic Liver Transplant Program in March 1985 to March 1995 1 decade later. Herein, we report the results of this study.