Role of nitric oxide synthesis in macrop
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Carl F. Nathan; John B. Hibbs Jr
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Article
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1991
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Elsevier Science
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English
โ 850 KB
Research over the past 5 years has demonstrated that immunologic activation of mouse macrophages induces the activity of nitric oxide synthase, which oxidizes a guanidino nitrogen of L-arginine, yielding citrulline and the reactive radical, nitric oxide. A review of the biochemistry and immunologic