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Factors that differentiate early vs. later onset of major depression disorder

✍ Scribed by Sidney Zisook; A. John Rush; Ari Albala; Jonathan Alpert; G.K. Balasubramani; Maurizio Fava; Mustafa Husain; Harold Sackeim; Madhukar Trivedi; Stephen Wisniewski

Book ID: 116848802
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 205 KB
Volume: 129
Category: Article
ISSN: 0165-1781
DOI: 10.1016/j.psychres.2004.07.004

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## Abstract Major depressive disorder (MDD) is a common, clinically heterogeneous disorder often found comorbid with other disorders. We studied recurrent, early‐onset MDD (MDD‐RE) and anxiety disorders in combination to define powerful phenotypes for genetic study. We used 87 large, extended Utah