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Factors regulating the induction of ornithine decarboxylase in fetal rat liver cells in culture

✍ Scribed by RUPNIAK, H; PAUL, D


Book ID
122931979
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
328 KB
Volume
543
Category
Article
ISSN
0304-4165

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Arizona 85724 DH23A cells, an a-difluoromethylornithine (DFMO)-resistant variant of rat hepatoma tissue culture cells (HTC), contain high levels of very stable ornithine decarboxylase (ODC). In the absence of DFMO, the high ODC activity results in a large accumulation of endogenous putrescine. Conco