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Factors influencing the protein binding of YH-439 using an equilibrium dialysis technique. A new hepatoprotective agent

✍ Scribed by Woo I. Lee; Woo H. Yoon; Joo H. Park; Jong W. Lee; Chang-K. Shim; Myung G. Lee

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 746 KB
Volume: 16
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.2510160907

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## Abstract Various factors influencing the protein binding of DA‐8159 to 4% human serum albumin (HSA) were evaluated using an equilibrium dialysis technique at an initial DA‐8159 concentration of 5 µg/mL. It took approximately 8 h incubation to reach an equilibrium between 4% HSA and an isotonic p