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Factors influencing the “in vitro” enhancement of l-asparaginase activity

✍ Scribed by Maureen B. Lee; C.Denise Bolger; J.M. Bridges

Book ID
115732546
Publisher
Elsevier Science
Year
1971
Weight
196 KB
Volume
242
Category
Article
ISSN
0005-2744

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L-asparaginase was effective in increasing the life span of leukemic (L5178Y) mice. However, the therapeutic effect of the drug was reduced when this treatment was preceded by a series of pretreatments (relative to tumor implantation) with the drug. T h e data from in vitro and in vivo studies revea