Factors governing the vulnerability of DRL operant performance to the effects of ethanol
β Scribed by Frank A. Holloway; Richard A. Wansley
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 707 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
β¦ Synopsis
The effects of various doses of ethanol on DRL performance was examined in rats under conditions of cued and non-cued DRL tasks and under conditions of low versus high baseline performance criteria. The dose-level at which ethanol produced a significant reduction in number of responses and reinforcements interacted in a complex fashion with level of baseline performance, the cue conditions, and the order of DRL tasks. Generally, performance was impaired at a lower dose level for groups initially trained to a low criterion of DRL performance than for groups later trained to a highel criterion of DRL performance, regardless of cue condition. Further, the dose level at which ethanol impaired performance (as indicated by number of reinforcements obtained) under non-cued DRL conditions was lower than that for the cued DRL conditions, but only on the initial task where baseline DRL performance criterion was lower. Finally, the group with a higher baseline level of responding (i.e., poorer Dt~L performance) was more vulnerable to the disrupting effects of ethanol on this measure than groups with lower baseline response rates.
π SIMILAR VOLUMES
Rats were trained to lever press on a differential reinforcement of low rates (DRL-18 s) schedule. They were then allocated to four treatment groups. These were: hippocampal aspiration lesions [HIPP]; implantation of osmotic minipumps for intraventricular infusion of either (a) the NMDA receptor ant