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Factors from glial cells regulate choline acetyltransferase and tyrosine hydroxylase activities in a hybrid-hybrid cell line

✍ Scribed by Rolf Heumann; Mücella Öcalan; Bernd Hamprecht


Book ID
115909691
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
434 KB
Volume
107
Category
Article
ISSN
0014-5793

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN