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Factors causing dose variability in drug administration

✍ Scribed by Romano Demicheli; Antonio Jirillo; Giorgio Bonciarelli; Federico Lonardi; Marco Pradella; Mario Balli


Publisher
Springer
Year
1989
Tongue
English
Weight
403 KB
Volume
24
Category
Article
ISSN
0344-5704

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Methodologically adequate clinical dose-response studies with antipsychotic compounds are reviewed. A number of consistent findings have emerged. Treatment resistant schizophrenics, and schizophrenics under 40, hospitalized less than 10 years often benefit from high or very high doses of antipsychot