Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease
β Scribed by Patricia A. Gabow; Ann M. Johnson; William D. Kaehny; William J. Kimberling; Dennis C. Lezotte; Irene T. Duley; Richard H. Jones
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 125 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0931-041X
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The results of classical segregation analysis on 159 families with polycystic kidney disease (PKD) are presented. It had been previously estimated that about 95% of autosomal dominant PDK (ADPKD) families have PKD 1, the gene localized to chromosome 16p. The main purpose of the study was to determin
Hepatic cysts are a major manifestation of autosomal dominant polycystic kidney disease. This study examined 239 autosomal dominant polycystic kidney disease patients and 189 unaffected family members to define the factors that influence the presence and severity of hepatic cysts. Autosomal dominant
## Background: Autosomal-dominant polycystic kidney disease (adpkd) is characterized by gradual renal enlargement and cyst growth prior to loss of renal function. standard radiographic imaging has not provided the resolution and accuracy necessary to detect small changes in renal volume or to relia