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Factors affecting the accuracy of estimated mean absorption times and mean dissolution times

โœ Scribed by Romulus K. Brazzell; Stanley A. Kaplan


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
346 KB
Volume
72
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


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The definitions of mean residence time of drug molecules in the body (MRT) from the literature are reviewed. A formal definition of MRT, based on excretion of drug molecules and amount of drug, a parameter which is independent of constancy of both clearance and volume of distribution, is introduced

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Mean transit times (MTTs) can give useful insights into the internal processes of hydrological systems. However, varying model conditioning assumptions and data availability can limit the use of MTT, particularly in terms of comparing the results of studies using different assumptions and data recor