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Factor XIII Val34Leu mutation accelerates the development of fibrosis in patients with chronic hepatitis B and C

✍ Scribed by Kathelijne Dik; Joep de Bruijne; R. Bart Takkenberg; Joris J. Roelofs; Marjan J. Tempelmans; Marcel G. W. Dijkgraaf; Huub C. Gelderblom; Henk W. Reesink; Joost C. M. Meijers; Peter L. Jansen; Marcel Levi


Book ID
114943993
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
377 KB
Volume
42
Category
Article
ISSN
1386-6346

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## Abstract Infection with hepatitis C virus (HCV) is associated with lymphoproliferative disorders, represented by essential mixed cryoglobulinemia and B‐cell non‐Hodgkin's lymphoma, but the pathogenic mechanism remains obscure. HCV may infect B cells or interact with their cell surface receptors,