✦ LIBER ✦

Factor X-activating procoagulant in normal and malignant breast tissue

✍ Scribed by Khaled El-Baruni; Irving Taylor; Stuart Roath; Dr. John L. Francis

Book ID: 102860152
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 602 KB
Volume: 8
Category: Article
ISSN: 0278-0232
DOI: 10.1002/hon.2900080604

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Factor X‐activating activity (FXAA) was determined by a chromogenic assay in normal and malignant breast tissue. FXAA was found in all tissue (n = 38) irrespective of pathology, and the activity of normal tissue was similar to that of tumours. FXAA correlated with tissue hemoglobin in normal breast (p<0.02) but not in tumours. FXAA was markedly reduced by aluminium hydroxide, barium citrate, anti‐human factor VII, DFP, PMSF and phospholipase C, but was unaffected by iodoacetamide and mercuric chloride. It is concluded that FXAA is a serine protease with the properties of a tissue factor‐factor VII complex. FXAA occurs in normal and malignant breast tissue, although the ‘normal’ activity may be an artefact of the homogenization process.

📜 SIMILAR VOLUMES

Collagen α1(XI) in normal and malignant

Collagen α1(XI) in normal and malignant breast tissue

✍ Halsted, Karen C; Bowen, Kara B; Bond, Laura; Luman, Sarah E; Jorcyk, Cheryl L; 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 399 KB

Midkine and pleiotrophin expression in n

Midkine and pleiotrophin expression in normal and malignant breast tissue

✍ Robert I. Garver Jr.; Diane M. Radford; Helen Donis-Keller; Mark R. Wick; Peter 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 805 KB

Background. Some growth factors may promote tumor growth by affecting tumor angiogenesis. The angiogenic growth factor, pleiotrophin, was demonstrated previously in human breast carcinoma tissues; however, the pattern of pleiotrophin expression in normal breast tissues has not been established. Met

Study of FHIT transcripts in normal and

Study of FHIT transcripts in normal and malignant breast tissue

✍ Ivan Bièche; Alain Latil; Véronique Becette; Rosette Lidereau 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 2 views

Cytogenetic and molecular studies have suggested that the 3p14.2 chromosome subband contains tumor suppressor genes involved in the pathogenesis of many types of human cancers. Recently, the FHIT (fragile histidine triad) gene was identified in this part of chromosome 3 as a candidate suppressor gen

P63 expression in normal, hyperplastic a

P63 expression in normal, hyperplastic and malignant breast tissues

✍ Xiaojuan Wang; Ichiro Mori; Weihua Tang; Misa Nakamura; Yasushi Nakamura; Misako 📂 Article 📅 2002 🏛 Springer Japan 🌐 English ⚖ 956 KB

Conversion to estriol in “normal”, benig

Conversion to estriol in “normal”, benign and malignant human breast tissues

✍ Rajeswari Seshadri; Nargis D. Bagli-Vania; J. N. Suraiya; Nandini A. Sheth 📂 Article 📅 1990 🏛 Springer-Verlag 🌐 English ⚖ 265 KB

Distribution and significance of nerve g

Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue

✍ Reis-Filho, Jorge S; Steele, Dawn; Di Palma, Silvana; Jones, Robin L; Savage, Ka 📂 Article 📅 2006 🏛 Nature Publishing Group 🌐 English ⚖ 996 KB