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Factor VII deficiency

โœ Scribed by Margaret V. Ragni; Jessica H. Lewis; Joel A. Spero; Ute Hasiba

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
532 KB
Volume
10
Category
Article
ISSN
0361-8609

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Factor VII (FVII) is a zymogen for a vitamin K-dependent serine protease essential for the initiation of blood coagulation. It is synthesized primarily in the liver and circulates in plasma at a concentration of approximately 0.5 microg/ml (10 nmol/L). The FVII gene (F7) is located on chromosome 13