The pathogenesis of venous thrombosis involves the interaction of genetic and environmental factors. In order to estimate the frequency of the factor V Leiden, the prothrombin G20210A, and the MTHFR C677T mutations in the Greek population, we analyzed 160 healthy Greek blood donors by PCR amplificat
Factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations among patients with sickle cell disease in Eastern Saudi Arabia
โ Scribed by Naglaa A. Fawaz; Layla Bashawery; Iman Al-Sheikh; Ahlam Qatari; Sara S. Al-Othman; Wassim Y. Almawi
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 58 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0361-8609
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๐ SIMILAR VOLUMES
## Objective: To evaluate the frequency and type of vascular lesions and to study the association of factor v gene g1691a (leiden) and prothrombin gene g20210a polymorphisms with venous thrombosis in italian patients with behรงet's disease (bd). ## Methods: Included were 118 consecutive italian bd
The prevalence of the prothrombin gene variant (allele 20.210 A), factor V Leiden mutation, and homozygosity for transition 677CโT in the methylenetetrahydrofolate reductase (MTHFR) gene was determined among patients with sickle cell disease (SCD). The group included 73 patients with median age of 3