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Factor J, an inhibitor of the classical and alternative complement pathway, does not inhibit esterolysis by factor D

✍ Scribed by Carolina González-Rubio; Rosario González-Mũniz; Miguel A. Jiménez-Clavero; Gumersindo Fontán; Margarita López-Trascasa


Book ID
113269829
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
414 KB
Volume
1295
Category
Article
ISSN
0167-4838

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Factor J, an inhibitor of the complement
✍ Miguel Angel Jiménez-Clavero; Carolina González-Rubio; Gumersindo Fontán; Margar 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 712 KB

Factor J (FJ) is a protein present in human serum, with inhibitory activity against C1. Here we describe the quantitation of FJ in human serum by means of an ELISA inhibition assay. We have purified FJ from the urine of a normal donor following a previously published method with slight modifications