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Factor H dysfunction contributes to platelet activation in hemolytic uremic syndrome (HUS)

✍ Scribed by Diana Karpman; Fariba Vaziri-Sani; Ann-Charlotte Kristoffersson; Anders G. Sjöholm; Peter F. Zipfel


Book ID
116756039
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
90 KB
Volume
44
Category
Article
ISSN
0161-5890

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We have studied the ability of the plasma to induce aggregation of both homologous and heterologous platelets in four patients with hemolytic-uremic syndrome (HUS) associated with chemotherapy with mitomycin C (MMC). Neither platelet aggregation was elicited by patients' plasmas nor the in vitro add