Factor Analysis Scales of Generalized Amino Acid Information as Applied in Predicting Interactions between the Human Amphiphysin-1 SH3 Domains and Their Peptide Ligands

Modeling and predicting interactions bet

Modeling and predicting interactions between the human amphiphysin SH3 domains and their peptide ligands based on amino acid information

✍ Jianfeng Cai; Rongying Ou; Yun-Sheng Xu; Li Yang; Zhihua Lin; Mao Shu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB

## Abstract In this paper, VHESH, which was a novel set of amino acid descriptors including hydrophobic, electronic, steric, and hydrogen bond contribution properties, were proposed to characterize the structures of the decapeptides binding the human amphiphysin‐1 Src homology 3 (SH3) domains, and