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Facilitated transdermal transport of insulin

✍ Scribed by Ovais Siddiqui; Ying Sun; Jue-Chen Liu; Yie W. Chien

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
573 KB
Volume
76
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

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## Abstract ## Background and Objective Previous studies have shown that photomechanical waves transiently permeabilize the stratum corneum in vivo. The aim of the present work was to investigate the potential of photomechanical waves for systemic drug delivery. ## Study Design/Materials and Meth

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Transdermal transport of insulin and extraction of interstitial glucose under anodal iontophoresis (electroosmosis) following electroporation in the presence of 1,2-dimyristoylphophatidylserine (DMPS) was studied. An earlier study showed that DMPS increased the transport of insulin across porcine ep