Facile synthesis of unsaturated lactones via intramolecular Wittig reaction
β Scribed by Pradeep Kumar; K. Saravanan
- Book ID
- 104208324
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 573 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
The phosphoranes 3 formed from the reaction of a variety of keto alcohols 1 and (triphenylphosphoranylidene)ethenone 2 undergo intramolecular Wittig cyclization to afford the unsaturated lactones in moderate yields. 0
π SIMILAR VOLUMES
## Abstract Treatment of triphenylphosphine with dialkyl acetylenedicarboxylate leads to 1:1 adduct and concomitant protonation of late adduct by pentanβ2,3,4βtrione 3βoxime gave the reactive intermediate, vinyltriphenylphosphonium salts, which undergoes an intramolecular Wittig reaction to produce
A systematic study of the intramolecular Wittig reactions of w-aldehydophosphoraaes 5 has been performed and indicates that the amounts of monounsaturated lactones 6 and dilactones 7 is dependent on chain length.