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Facile Synthesis of 4-Substituted-2-quinolinone-3-carboxylic Acid Ethyl Esters

✍ Scribed by Zhang, Lijuan; Luo, Yu; Yu, Shanbao; Lu, Wei


Book ID
118762884
Publisher
Journal of Heterocyclic Chemistry
Year
2012
Tongue
English
Weight
138 KB
Volume
49
Category
Article
ISSN
0022-152X

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Facile Synthesis of Substituted Ethyl 2-
✍ Bhimapaka China Raju; Gannerla Saidachary; Jaladi Ashok Kumar; Balasubramanian S πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 German βš– 213 KB

## Abstract Ethyl 2‐(chloromethyl)‐2‐hydroxy‐2__H__‐chromene‐3‐carboxylates **2a**–**2j** have been synthesized by reaction of substituted salicylaldehydes with ethyl 4‐chloro‐3‐oxobutanoate, in the presence of piperidine in CH~2~Cl~2~ at room temperature, in good yields.