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Facile Synthesis of 4- H -Pyran Derivatives Bearing Indole Skeleton via [3+3] Cyclization of 3-Indolyl-3-oxopropanenitriles with Dialkyl Acetylenedicarboxylates and Isocyanides

✍ Scribed by Song, Ping; Zhao, Lili; Ji, Shunjun


Book ID
121864178
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
610 KB
Volume
32
Category
Article
ISSN
0256-7660

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One-Step Synthesis of Dialkyl 2-[(4-Meth
✍ Abdolali Alizadeh; Hassan Masrouri; Sadegh Rostamnia; Farnaz Movahedi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 61 KB

## Abstract The reactive 1 : 1 adducts in the reaction between Ph~3~P and dialkyl acetylenedicarboxylates have been trapped with ‘tosylmethyl isocyanide’ (TsMIC; **1**) to yield dialkyl 2‐[(4‐methylphenyl)sulfonyl]‐1__H__‐pyrrole‐3,4‐dicarboxylates **3** (__Scheme 1__). The structures of the highly