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Facile rearrangement of N4-(α-aminoacyl)cytidines to N-(4-cytidinyl)amino acid amides

✍ Scribed by Deyi Zhang; David M. Bender; Frantz Victor; Jeffrey A. Peterson; Robert D. Boyer; Gregory A. Stephenson; Adam Azman; James R. McCarthy


Book ID
108284853
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
195 KB
Volume
49
Category
Article
ISSN
0040-4039

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N-Acetyl-2-(p-phenetidino)-3-cyano-5.~6~7,8-tetrahydroquinoline (lllg). A mixture of 1.92 g (0.01 mole) of (I) and 0.01 mole of N-acetyl-p-phenetidine was heated for 6 h at 190~ treated with hot water, and the solid filtered off and crystallized from ethanol to give 1.21 g (63%) of product, mp I15-I