Facile preparation of chloromethylaryl solid supports using methanesulfonyl chloride and Hunig's base

✦ Synopsis

Several commercially available hydmxymethylaryl resins were converted to their correslmqading chloromethyl analogs by simple treatment with methanesuifonyl chloride and Hunig's base in DMF at 25 *(2 over 3 days. This mild method gave quantitative conversions as deamnined by elemental analysis and 13C NMR.

Should solid-state molecular packing hav

Should solid-state molecular packing have to obey the rules of crystallographic symmetry?This article is based (partly) on a presentation which will be made at the European Research Conference (EURESCO) on "Molecular Crystal Engineering - EuroConference on Design and Preparation of Molecular Materials" (Acquafredda di Maratea, Italy, 31 May - 5 June 2003) organised by the European Science Foundation and supported by the European Commission, Research DG, Human Potential Programme, High-Level Scientific Conferences, Contract HPCF-CT-2002-00270. This information is the sole responsibility of the author(s) and does not reflect the ESF or Community's opinion. The ESF and the Community are not responsible for any use that might be made of data appearing in this publication.

✍ Steed, Jonathan W. 📂 Article 📅 2003 🏛 Royal Society of Chemistry 🌐 English ⚖ 591 KB