Facile one-pot synthesis of α-amino phosphonates using lanthanide chloride as catalyst

✍ Scribed by Fan Xu; Yiqin Luo; Jianting Wu; Qi Shen; Hou Chen

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 98 KB
• Volume: 17
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20219

✦ Synopsis

An efficient preparation of ␣-amino

phosphonates by the one-pot condensation of aldehydes, amines, and dialkyl phosphites using catalytic amounts of lanthanide chloride under mild conditions is successfully developed. Moreover, the catalyst is water-tolerant and could be recovered and reused.