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Facile One-Pot Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles through Sonogashira Coupling/1,3-Dipolar Cycloaddition of Acid Chlorides, Terminal Acetylenes, and Sodium Azide

✍ Scribed by Li, Jihui; Wang, Dong; Zhang, Yuanqing; Li, Jiting; Chen, Baohua

Book ID
120035010
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
364 KB
Volume
11
Category
Article
ISSN
1523-7060

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ChemInform Abstract: One-Pot Synthesis o
ChemInform Abstract: One-Pot Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles Using Terminal Acetylenes, Carbon Monoxide, Aryl Iodides, and Sodium Azide.
✍ Na Li; Dong Wang; Jihui Li; Weilin Shi; Chao Li; Baohua Chen πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 1 views

## Abstract The alkynes, CO and the aryl iodides undergo Pd‐catalyzed carbonylative Sonogashira reaction to yield an alkynone intermediate which is directly coupled with azide to give the title triazoles.