✦ LIBER ✦
Facile Nucleophilic Silylation Reactions at Carbonyl Functionalities Using Trimethylsilylaluminum Compounds
✍ Scribed by Priv.-Doz. Dr. Lutz Rösch; Dr. Gerald Altnau; Dr. Wolfgang Helmut Otto
- Book ID
- 101552151
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 232 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
✦ Synopsis
In order to check whether organic compounds can be nucleophilically silylated with Me~3~SiAl compounds such as (1) and (2), the latter were allowed to react with an aldehyde, a ketone, and an acid. Complexing agents like diethyl ether and AlCl~3~ have considerable influence on the reactions. Summary: Reagents (1) and (2) can be used for the directed nucleophilic silylation of carbonyl compounds; α‐hydroxytrimethylsilyl derivatives are formed. An advantage is the absence of undesirable by‐products.
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