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Facile formation of N-alkyl-oxazolidin-2-ones from N-alkyl-nitroxyethylamines and carbonate anion in biphasic media

✍ Scribed by Michael E. Sitzmann; James A. Kenar; Nirupam J. Trivedi


Book ID
108387120
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
134 KB
Volume
39
Category
Article
ISSN
0040-4039

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At room temperature, the presence of hydrogen and catalytic amounts of Pd/C induced the formation of 1,3-oxazolidines from nitriles and 1,2-amino alcohols. The subsequent reductive cleavage of the NC-O bond of lhese heterocycles occurred under the same conditions. Thus, this methodology provides a n