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Facile Enantioselective Synthesis of Propargylic Alcohols by Direct Addition of Terminal Alkynes to Aldehydes

✍ Scribed by Frantz, Doug E.; Fässler, Roger; Carreira, Erick M.

No coin nor oath required. For personal study only.

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The enantioselective synthesis of propargylic alcohols was achieved by enantioselective allyltitanation of acetylenic aldehydes.

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