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Facile cleavage of C–C bond: conversion of pyrane derivative to 1,3-oxazin derivative

✍ Scribed by Zhilan Lin; Xueli Zhang; Xinkui You; Yuan Gao


Book ID
116909521
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
448 KB
Volume
68
Category
Article
ISSN
0040-4020

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Cyclization reactions of tricarbonylmeth
✍ Somogyi, László 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB

Under acylating conditions 3-acetyl-4-hydroxy-2H-pyran-2one thiosemicarbazones (la, b and 2a, b) are transformed into 2-(acylamino)-5-methyl-1,3,4-thiadiazoles 3b, c, e, f and 2H-pyran-2-ones l c and 2 c via C-C bond cleavage. Similarly, the reaction of lb with RC02H/EtOH (R = Me, Et) af-fords 2-ani