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Facile Approach to 4-Substituted 2(5 H )-Furanones

✍ Scribed by Yao, Min-Liang; Deng, Min-Zhi


Book ID
125940706
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
64 KB
Volume
65
Category
Article
ISSN
0022-3263

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## Abstract Highly optically active 4‐substituted‐2(5__H__)‐furanones 6a‐6j were obtained in good yields with __de__β©Ύ98% by the tandem Michael addition/elimination reaction of chiral 3‐bromo‐2(5__H__)‐furanone (4a), which was conveniently prepared starting from 2‐furaldehyde under mild conditions.