Facile and efficient synthesis of fluoroalkyl aryl ethers

✍ Scribed by Ahmed Kamal; T.B Pratap; K.Venkata Ramana; A.V Ramana; A.Hari Babu

• Book ID: 104251995
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 107 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01719-7

✦ Synopsis

A convenient and practical method for the preparation of fluoroalkyl aryl ethers via substitution of iodoalkyl fluorides is described. This method involves KF complexation of the phenol, which increases the nucleophilicity of oxygen for the formation of the ether linkage.