Transdermal delivery of naltrexol and sk
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Stan L. Banks; Raghotham R. Pinninti; Harvinder S. Gill; Kalpana S. Paudel; Pete
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Article
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2010
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John Wiley and Sons
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English
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Controlled-release delivery of 6-beta-naltrexol (NTXOL), the major active metabolite of naltrexone, via a transdermal patch is desirable for treatment of alcoholism. Unfortunately, NTXOL does not diffuse across skin at a therapeutic rate. Therefore, the focus of this study was to evaluate microneedl