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Face-Selective Addition to a Cation−π Complex of a Pyridinium Salt: Synthesis of Chiral 1,4-Dihydropyridines

✍ Scribed by Yamada, Shinji; Morita, Chisako


Book ID
119967597
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
98 KB
Volume
124
Category
Article
ISSN
0002-7863

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Synthesis of chiral 1,4-dihydropyridines
✍ Shinji Yamada; Mayumi Ichikawa 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 227 KB

Diastereoface-selective asymmetric addition of organometallic reagents to pyridinium salts of 1 and 2 was performed to give chiral 1,4-dihydropyridines in good regio-and stereoselectivities. The absolute configuration of the newly-produced chiral center was determined by X-ray analysis after derivat

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