Fabrication of sample target plate for MALDI-TOF MS using proton beam writing

Microscale sample deposition onto hydrop

Microscale sample deposition onto hydrophobic target plates for trace level detection of neuropeptides in brain tissue by MALDI-MS

✍ Hui Wei; Stacey L. Dean; Mark C. Parkin; Kerstin Nolkrantz; James P. O'Callaghan 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 549 KB

## Abstract A sample preparation method that combines a modified target plate with a nanoscale reversed‐phase column (nanocolumn) was developed for detection of neuropeptides by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS). A gold‐coated MALDI plate wa