Fabrication of polymeric micelles with core–shell–corona structure for applications in controlled drug release

Fabrication of Complex Micelles with Tun

Fabrication of Complex Micelles with Tunable Shell for Application in Controlled Drug Release

✍ Chenglin Wu; Rujiang Ma; Huan He; Lizhi Zhao; Hongjun Gao; Yingli An; Linqi Shi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 517 KB

## Abstract At room temperature, diblock copolymers of PLA‐__b__‐PNIPAM and PEG‐__b__‐PLA self‐assembled into complex micelles with a PLA core and a mixed PEG/PNIPAM shell. By increasing the temperature, these complex micelles could be converted into a core‐shell‐corona structure composed of a PLA