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Fabrication of DNA electrochemical biosensor based on gold nanoparticles, locked nucleic acid modified hairpin DNA and enzymatic signal amplification

✍ Scribed by Xiaomeng Meng; Minrong Xu; Jianying Zhu; Huanshun Yin; Shiyun Ai

Book ID
113596804
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
588 KB
Volume
71
Category
Article
ISSN
0013-4686

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## Abstract In this work, we report on the preparation of a simple, sensitive DNA impedance sensor. Firstly gold nanoparticles were electrodeposited on the surface of a gold electrode, and then probe DNA was immobilized on the surface of gold nanoparticles through a 5′‐thiol‐linker. Electrochemical