## Abstract In 2004, Shen et al. developed a safe and efficient gene transfer system using a DNA‐apatite composite layer. We have recently succeeded in improving further the gene transfer efficiency by immobilizing a cell adhesion molecule laminin, in a DNA‐apatite composite layer. In this study, w
✦ LIBER ✦
Fabrication of a DNA-lipid-apatite composite layer for efficient and area-specific gene transfer
✍ Scribed by Ayako Oyane; Yushin Yazaki; Hiroko Araki; Yu Sogo; Atsuo Ito; Atsushi Yamazaki; Hideo Tsurushima
- Book ID
- 113070183
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 496 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0957-4530
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Gene transfer techniques are useful tools for controlling cell behavior, such as proliferation and differentiation. We have recently developed an efficient area-specific gene transfer system using a DNA efibronectineapatite composite layer (DF-Ap layer). In this system, partial dissolution of the co