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Fabrication and in vitro evaluation of alginate–methotrexate microspheres

✍ Scribed by S. Afifi; S. Alipour; H. Montaseri

Book ID
103849651
Publisher
Elsevier
Year
2009
Tongue
English
Weight
67 KB
Volume
25
Category
Article
ISSN
1871-6784

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## Abstract Mucoadhesive alginate microspheres of carvedilol (CRV) for nasal administration intended to avoid first pass metabolism and to improve bioavailability were prepared and evaluated. The microspheres were prepared by emulsification cross‐linking method. Radiolabeling of CRV and its microsp