𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fabrication and analysis of ionic conductive polymer films for micro drug delivery systems

✍ Scribed by Nan-Chyuan Tsai; Chung-Yang Sue


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
781 KB
Volume
141
Category
Article
ISSN
0924-4247

No coin nor oath required. For personal study only.

✦ Synopsis


Dynamic analysis of well-bonding sandwich-alike driving diaphragms, made of ionic conductive polymer (ICP), and an innovative fabrication technique to micro-machine them are reported. Firstly, the dynamics of ICP film (ICPF), serving as an actuator, is theoretically studied and described in governing equation via chemical and mathematical analysis. The purpose is to explore the explicit expression in differential equation upon the direct connection of the induced lateral deflection of ICPF with respect to exerted electrical field. This is the first major issue of this paper: output/input relation. The other major issue is its fabrication technology. That is, the structure layers, made of polydimethylsiloxane (PDMS), and the sandwiched ICPF are successfully integrated as a monolithic driving actuator by an innovative fabrication technique. As for technology, there are three challenging targets to be well achieved. First of all, the novel method to fabricate ICPF actuators is well developed to overcome conventionally insufficient adhesion of added-externally electrodes upon ICPF. Secondly, the ICPF has to be kept right straight and flat as it is fabricated, even though its thickness is far less than its length. Lastly, the ICPF has to function in aqueous environment that is fully taken into consideration at the stage of fabrication.


πŸ“œ SIMILAR VOLUMES


Simultaneous and sequential micro-porous
✍ T. Thimma Reddy; Atsushi Takahara πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 1000 KB

Novel semi-interpenetrating polymer networks (so-called simultaneous SIPNs) of various compositions were synthesized using segmented polyurethane urea (SPUU), N-isopropylacrylamide (NIPAM), acrylic acid (AA), and butylmethacrylate (BMA), resulting in an SIPN film denoted as SPUU/poly(NIPAM-co-AAco-B

Bioresorbable nanofiber-based systems fo
✍ Katti, Dhirendra S. ;Robinson, Kyle W. ;Ko, Frank K. ;Laurencin, Cato T. πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 408 KB

## Abstract Wound healing is a complex process that often requires treatment with antibiotics. This article reports the initial development of a biodegradable polymeric nanofiber‐based antibiotic delivery system. The functions of such a system would be (a) to serve as a biodegradable gauze, and (b)

Fabrication of dissolving polymer micron
✍ Leonard Y. Chu; Seong-O Choi; Mark R. Prausnitz πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 233 KB

Dissolving microneedle patches offer promise as a simple, minimally invasive method of drug and vaccine delivery to the skin that avoids the need for hypodermic needles. However, it can be difficult to control the amount and localization of drug within microneedles. In this study, we developed novel

Polymers and drugs suitable for the deve
✍ Marian LΓΆbler; Katrin Sternberg; Oliver Stachs; Reto Allemann; Niels Grabow; Ann πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 391 KB πŸ‘ 2 views

## Abstract Implantation of a glaucoma drainage system is an appropriate therapeutic intervention in some glaucoma patients. However, one drawback with this approach is the fibrotic tissue response to the implant material, leading to reduced flow of aqueous liquid or complete blockage of the draina