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FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

✍ Scribed by Ling, Chen; Ishiai, Masamichi; Ali, Abdullah Mahmood; Medhurst, Annette L; Neveling, Kornelia; Kalb, Reinhard; Yan, Zhijiang; Xue, Yutong; Oostra, Anneke B; Auerbach, Arleen D


Book ID
110032040
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
378 KB
Volume
26
Category
Article
ISSN
0261-4189

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The DAC2/FUS3 protein kinase is not esse
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The DAC2/FUS3 gene of Saccharomyces cerevisiae, which encodes a CDC28/cdc2-related protein kinase, is essential both for the arrest of cell division induced by mating pheromones and for cell fusion during conjugation. To elucidate the role of the DAC2 gene product in the pheromone response pathway,