✦ LIBER ✦

F.31. Lost Inhibitions? T Cell Activation Pathways in SLE

✍ Scribed by Deborah Cunninghame Graham; Philippe Goyette; Robert Graham; Kathy Moser; Patrick Gaffney; Alexandre Montpetit; Lauren Chad; Thomas Hudson; David Altshuler; Paul Fortin; Joan Wither; Tim Behrens; John Rioux; Timothy Vyse

Book ID: 113541052
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 42 KB
Volume: 131
Category: Article
ISSN: 1090-2341
DOI: 10.1016/j.clim.2009.03.297

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Proteasome inhibition activates the mito

Proteasome inhibition activates the mitochondrial pathway of apoptosis in human CD4+ T cells

✍ Carsten Berges; Heinrich Haberstock; Dominik Fuchs; Mahmoud Sadeghi; Gerhard Ope 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 420 KB 👁 1 views

## Abstract We have previously shown that inhibition of the proteolytic activity of the proteasome induces apoptosis and suppresses essential functions of activated human CD4^+^ T cells, and we report now the detailed mechanisms of apoptosis following proteasome inhibition in these cells. Here we s

Defects of mitogen-activated protein kin

Defects of mitogen-activated protein kinase in ICOS signaling pathway lead to CD4+ and CD8+ T-cell dysfunction in patients with active SLE

✍ Cai Gang; Yang Jiahui; Wang Huaizhou; Cai Qing; Zhao Dongbao; Shen Qian 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 771 KB

Inhibition of NAMPT pathway by FK866 act

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells

✍ Basant Kumar Thakur; Tino Dittrich; Prakash Chandra; Annette Becker; Yannick Lip 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 405 KB

Curcumin induces growth-arrest and apopt

Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK–STAT pathway in T cell leukemia

✍ Johnson Rajasingh; Himanshu P. Raikwar; Gladson Muthian; Caroline Johnson; John 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 568 KB

cAMP-dependent protein kinase (PKA) inhi

cAMP-dependent protein kinase (PKA) inhibits T cell activation by phosphorylating Ser-43 of Raf-1 in the MAPK/ERK pathway

✍ Charlotte Ramstad; Vibeke Sundvold; Heidi K. Johansen; Tor Lea 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 233 KB

High-density lipoproteins inhibit inflam

High-density lipoproteins inhibit inflammatory pathways in human monocytes activated upon chronic inflammatory conditions by cellular contact with stimulated T cells

✍ Danielle Burger; Lyssia Gruaz; Jean-Michel Dayer 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 46 KB